Biomaterials – The Next Revolution

Up to 60% of global physical inputs could eventually be produced through biological processes — from food and textiles to packaging and energy.

Commercially viable use cases include fermented proteins, lab-grown collagen, omega-3s from algae, and biodegradable packaging.

Bio-based nutraceuticals are seeing explosive consumer interest, especially in functional foods, microbiome health, and longevity markets.

Convergence of biology + technology is enabling cost-competitive, sustainable biomaterials across multiple sectors which are scalable, and investable solutions to global industrial challenges.

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Biodegradable Solutions

  • Biomaterials are derived from renewable sources, can be composted or biodegraded, and have a significantly reduced carbon footprint. (Market Determinant)

  • Consumers and companies alike are demanding more sustainable, traceable, and natural alternatives, creating a strong market pull. (Pull)

  • Advances in gene editing, automation, and cell engineering have made it faster and cheaper to design and produce new biomaterials. (Push)

However, there are industry level challenges with questions on –

  • Scalability and cost-effectiveness (Is it better than current non renewable derivative?)

  • Material properties and performance (consistency and varied end-use application)

  • End-of-life management and biodegradation (non-toxic but needs guidelines)

  • Regulatory frameworks and standards (undefined)

Market Size – Scale of Impact

Where we fit in – Natural Biomaterials segment which will witness 13% CAGR (relatively higher than other sub-segments) and relevant to our experience.

What developed so far – Melanin (99.9%+ purity) and Chitosan (derivatives with wide spectrum).

Efforts to Commercialise – Initial labs and operations set-up in India with support from Venture Centre and smaller orders being fulfilled right now.

Confidence to Scale – Samples of higher quality rather than common alternatives with c. 45% reduced costs. We would disrupt the market with the quality and consistency which is non-existent for now.

Biomaterials Market – By Type of Product (2019 – 2035 US$ Billion)
7.9% CAGR Till 2035
USD 193 Billion – Current Market Size
USD 442 Billion – Value in 2035

The economic potential is significant, with a projected $2 to $4 trillion in annual impact by 2030–2040.

Biomaterials - Melanin

The successful interfacing of electronics with biology is the next frontier for microelectronics and nanotechnology.

Melanin, a naturally occurring conjugated polymer composed of different structural subunits, may be an ideal candidate for such interfacing. 

https://www.sciencedirect.com/science/article/abs/pii/S0956566318307176
https://www.frontiersin.org/news/2019/03/26/will-cyborgs-circuits-be-made-from-melanin/

What is Melanin?
A naturally occurring biopolymer with unique ionic-electronic conductivity, biocompatibility, and environmental resilience — offering a novel platform for next-gen electronic materials.

PropertyImpact in Tech
Biocompatible & biodegradableIdeal for implantables, wearables, and medical electronics
Mixed electron–ion conductivityEnables bioelectronic interfaces, neural stimulation, and biosignal capture
Self-healing & photoprotectiveDurable in hostile or flexible environments
Broad-spectrum light absorptionValuable for photodetectors, UV sensors, solar harvesting

Confined mostly in Research Labs & through Non-Scalable sources

While abundant in nature, globally there lacks a way to extract 100% water-soluble melanin in large enough quantities to allow melanin’s applications to begin commercialisation.

Naturally Derived

  • Animals and Human – Hair/Skin/Eyes

  • Cuttlefish Ink

Synthetically Driven

  • Black Garlic

  • Bacteria & Fungi – Extra and Endo-cellular

Promecens patentable process has output result c. 500 times more in quantity than standard extraction process and the output product to be achieved at 99.9%+ purity levels.

All the steps to extract Melanin is effective for limited extraction and remains cost ineffective.

Intrinsic Properties (COA Available)

  • Scientifically – Heterogeneous biopolymer composed of indole units – 5,6-dihydroxyindole (DHI) and carboxylated derivate DHICA.

  • Hydration-dependent conductivity, meaning conducts significantly when “wet”.

  • Broadband absorber (UV–visible), a stable free-radical scavenger, and resists photodegradation, indicating good environmental and radiative stability.

  • Operationally scalable with fully automated solution has been validated for end-to-end process albeit at very small scale.

  • Quantities produced so far – 2,000 grams+ where the retail value lies between €800 – €1,200 per gram.

Where we lack – Commercialization and EU Standards Certified manufacturing (hence looking to scale through Ireland) and pushing for securing more LOIs.

Actual Image from Melanin Production Process

Melanin Agenda – Climate Viable, Profitable to Scale

AspectMicrobial Melanin (Fungi/Bacteria)Traditional/Synthetic Melanin (Sepia/callus/chemical)
Feedstock SourceRenewable: microbes using low-cost carbon sources or wastesAnimal-derived (e.g. cuttlefish ink) or plant callus; or petroleum-based chemical synthesis
Production Scale & YieldIncreasing via strain selection and fermentationTraditionally limited by resource availability; synthetic cost and scale constraints
Extraction IntensityMild: biochemical fermentation, enzymatic or mechanical separationCan be harsh: involves solvents and complex purification steps, especially from animal/plant tissues
Environmental ImpactGenerally lower: uses renewable inputs and less chemical use; potential for climate-positive with circular feedstocksHigher impact: marine harvesting, solvent use, or fossil inputs; more energy-intensive
Functional BenefitsHigh bioactivity, customizable via strain engineering and process controlEffective as pigment, but less versatile in tuning properties
Climate-Positive PotentialHigh: biomaterial-based, low waste, renewable feedstocksLow: more conventional, limited circularity, higher carbon footprint
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